Pulsed Field Ablation vs. Cryoballoon Ablation in Patients With Persistent Atrial Fibrilla
This clinical study is being conducted to compare two different treatment methods for persistent atrial fibrillation (AF), a common heart rhythm disorder. Atrial fibrillation occurs when the upper chambers of the heart (the atria) beat rapidly and irregularly. This can lead to symptoms like palpitations, shortness of b
| Condition(s) | Persistent Atrial Fibrillation |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This clinical study is being conducted to compare two different treatment methods for persistent atrial fibrillation (AF), a common heart rhythm disorder. Atrial fibrillation occurs when the upper chambers of the heart (the atria) beat rapidly and irregularly. This can lead to symptoms like palpitations, shortness of breath, or fatigue, and it increases the risk of stroke or heart failure. Persistent atrial fibrillation means that the irregular heart rhythm continues and does not stop on its own. Treatment often includes a procedure called catheter ablation, where special instruments are used to create small scars in the heart to block the abnormal electrical signals causing the arrhythmia. Currently, two main types of catheter ablation are used in Japan: Cryoballoon Ablation: A technique |
| Who can participate | Inclusion Criteria: * Age between 18 and 85 years * Diagnosed with PeAF (lasting less than one year or requiring cardioversion) * Eligible for catheter ablation according to current Japanese guidelines * Provided written informed consent Exclusion Criteria: * Paroxysmal or long-standing persistent AF (duration \>1 year) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Lead sponsor | Kitasato University |
| Locations | Sagamihara, Kanagawa, Japan |
| Start date | 2025-06-25 |
| NCT ID | NCT07064616 |
| Official listing | https://clinicaltrials.gov/study/NCT07064616 |