Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Sta
Investigators' overall objective is to compare methods of identifying individuals who may be experiencing challenges in Cognitive Processing Therapy (CPT) and compare methods of intervening to optimize treatment retention and outcomes. Investigators' specific aims are: 1. to determine whether the use of CPT skills vers
| Condition(s) | Post Traumatic Stress Disorder |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Investigators' overall objective is to compare methods of identifying individuals who may be experiencing challenges in Cognitive Processing Therapy (CPT) and compare methods of intervening to optimize treatment retention and outcomes. Investigators' specific aims are: 1. to determine whether the use of CPT skills versus collaboratively considering switching to Present Centered Therapy (PCT) is more effective in improving outcomes for individuals experiencing challenges with CPT. Outcomes include post-traumatic stress disorder (PTSD) severity \[primary\], depression, functioning, and treatment retention; 2. to compare two approaches to identifying individuals in CPT in need of additional support during treatment; 3. to study the barriers and facilitators of implementing these intervention |
| Who can participate | Inclusion Criteria: * Veterans interested in outpatient VA psychotherapy for PTSD * Meets DSM-5 criteria for PTSD * Be able to provide informed consent * Be willing to be randomized * Agree to not receive non-study psychotherapy for PTSD during study treatment (case management, supportive therapy/group, and concurrent substance use treatment are allowable) Exclusion Criteria: * Severe cognitive impairment * Current suicidal or homicidal intent with a specific plan * Uncontrolled psychotic or manic symptoms * A psychiatric medication change in the past month * A severe SUD as diagnosed by the DSM-5 |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | United States Department of Defense |
| Locations | Phoenix, Arizona, United States; New Orleans, Louisiana, United States; Charleston, South Carolina, United States; Houston, Texas, United States |
| Start date | 2025-03-17 |
| NCT ID | NCT06957067 |
| Official listing | https://clinicaltrials.gov/study/NCT06957067 |