Remifentanil and Remimazolam to Limit Patient Movement
Local anesthetics (LA) may be administered by injection (retrobulbar, peribulbar, subconjunctival, lid, or facial block) or by instillation (topical anesthesia), Considerable drawbacks of local anesthesia in these patients include the fact that a few patients can remain comfortable on an operating table for procedures
| Condition(s) | Long-Eye Surgeries |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Local anesthetics (LA) may be administered by injection (retrobulbar, peribulbar, subconjunctival, lid, or facial block) or by instillation (topical anesthesia), Considerable drawbacks of local anesthesia in these patients include the fact that a few patients can remain comfortable on an operating table for procedures that exceed two or three hours. Sedation may be helpful with LA to decrease the experience of discomfort, movement and anxiety, which may in turn positively influence hemodynamic parameters, patient satisfaction, and overall improve surgical safety. Sedatives used in eye surgeries include benzodiazepines, opioids, alpha-adrenoceptor agonists, and propofol. |
| Who can participate | Inclusion Criteria: * Age \> 40 years. * Both sexes. * American Society of Anesthesiology (ASA) physical status I-III. * Undergoing long-eye surgeries under local anesthesia using peribulbar block with an expected surgical time of more than one hour. Exclusion Criteria: * Patients on aspirin or anticoagulants. * Allergy to any study medication. * Drug abuse. * Uncontrolled hypertension. * Hyperthyroidism. * Frequent cough. * Impaired hearing. * Severe liver and kidney dysfunction. * Neurological or psychological disorders. * Partial or failed block. |
| Ages | 40 Years to 50 Years |
| Sex | All |
| Lead sponsor | Egymedicalpedia |
| Locations | Cairo, Egypt |
| Start date | 2024-07-10 |
| NCT ID | NCT06583811 |
| Official listing | https://clinicaltrials.gov/study/NCT06583811 |