Resting Full-cycle Ratio (RFR)-Guided Revascularization
The purpose of this study is to compare the clinical outcomes of a 2-year follow-up to determine whether RFR-guided coronary intervention is non-inferior to FFR-guided coronary intervention in patients with intermediate coronary stenosis.
| Condition(s) | Coronary Artery Disease |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The purpose of this study is to compare the clinical outcomes of a 2-year follow-up to determine whether RFR-guided coronary intervention is non-inferior to FFR-guided coronary intervention in patients with intermediate coronary stenosis. |
| Who can participate | Inclusion Criteria: * Patients with intermediate coronary artery stenosis (visually 50-90% diameter stenosis) who decided to undergoing a RFR-guided coronary intervention according to clinical necessity * Patients who voluntarily decided to participate in this study and signed informed consent Exclusion Criteria: * Severe left ventricular systolic dysfunction (LVEF \<30%) * Cardiogenic shock * Culprit vessel in acute coronary syndrome * Donor vessel to supply chronic total occlusion lesion of non-target vessel * Symptomatic valvular heart disease or cardiomyopathy * Hemodynamic instability at the time of intervention (heart rate \<50 beats per minute, systolic blood pressure \<90mmHg) * Previous CABG with patent grafts to the interrogated vessel * Pregnancy or breastfeeding * Non-cardiac c |
| Ages | 20 Years to 90 Years |
| Sex | All |
| Lead sponsor | Sejong General Hospital |
| Locations | Bucheon-si, Gyeonggi-do, South Korea |
| Start date | 2022-07-27 |
| NCT ID | NCT06075160 |
| Official listing | https://clinicaltrials.gov/study/NCT06075160 |