Retinoblastoma Patient Clinical Database and Tissue Repository
Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed. Given this limitation, we use aqueous humor (AH), the clear fluid in the front of the eye to detect s
| Condition(s) | Retinoblastoma, Retinoblastoma Bilateral, Retinoblastoma Unilateral |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed. Given this limitation, we use aqueous humor (AH), the clear fluid in the front of the eye to detect specific markers, or information, that comes from the tumor itself. |
| Who can participate | Inclusion Criteria: * All patients, age 0 days to 18 years, with a diagnosis unilateral or bilateral retinoblastoma (RB) seen at CHLA (Children's Hospital Los Angeles). Exclusion Criteria: * Patients referred for second opinions only and not treated at CHLA for any reason. |
| Ages | 0 Years to 18 Years |
| Sex | All |
| Lead sponsor | Children's Hospital Los Angeles |
| Locations | Phoenix, Arizona, United States; Los Angeles, California, United States; Atlanta, Georgia, United States; Chicago, Illinois, United States; Portland, Oregon, United States; Philadelphia, Pennsylvania, United States (+3 more sites) |
| Start date | 2017-01-01 |
| NCT ID | NCT04959097 |
| Official listing | https://clinicaltrials.gov/study/NCT04959097 |