Rheumatoid Arthritis and Osteosarcopenia: Associated Factors
Our study is a cross-sectional study, and its aim is to compare and analyze the prevalence of sarcopenia and osteoporosis in patients with rheumatoid arthritis (RA) with a control group and to reveal the impact of sarcopenia on osteoporosis, fall risk, and fracture risk. This prospective cross-sectional study will incl
| Condition(s) | Osteosarcopenia, Rheumatoid Arthritis (RA), Sarcopenia |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Our study is a cross-sectional study, and its aim is to compare and analyze the prevalence of sarcopenia and osteoporosis in patients with rheumatoid arthritis (RA) with a control group and to reveal the impact of sarcopenia on osteoporosis, fall risk, and fracture risk. This prospective cross-sectional study will include 100 rheumatoid arthritis patients and 100 healthy controls, matched for age and sex. Patients will be consecutively and meticulously enrolled based on inclusion and exclusion criteria. A detailed medical history and examination will be performed on the patients, and their clinical and sociodemographic characteristics will be recorded. Blood tests for RA (RF, Anti-Cyclic Citrullinated Peptide (anti-CCP), CRP, ESR) and disease activity levels (DAS28) will be recorded. The p |
| Who can participate | Inclusion criteria: 1. Being diagnosed with RA according to the ACR/EULAR 2010 criteria 2. Being a female or male over the age of 50 3. Having the mental and physical capacity to complete the study questionnaires and tests 4. Providing voluntary consent to participate in the study by signing the Informed Consent Form Exclusion Criteria: 1. Having an acute illness/disability or significant cognitive impairment that prevents understanding and performing the required tests 2. Having thyroid or parathyroid disease, uncontrolled diabetes, Cushing's syndrome, anemia. 3. History of malignancy 4. Severe cardiovascular disease, enal failure, advanced-stage COPD, decompensated liver disease 5. History of gastrointestinal (GIS) surgery 7-Having another coexisting autoimmune/inflammatory rheumatic dis |
| Ages | 50 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Konya Beyhekim Training and Research Hospital |
| Locations | Konya, Selçuklu, Turkey (Türkiye) |
| Start date | 2023-08-15 |
| NCT ID | NCT06889415 |
| Official listing | https://clinicaltrials.gov/study/NCT06889415 |