Risk Factors for Complications After Cranioplasty
Cranial defects often result from brain injuries, hemorrhages, strokes, or brain tumors. These conditions can increase pressure inside the skull, and if left untreated, may lead to dangerous complications like brain herniation. To manage this, a common procedure called decompressive craniectomy is performed to reduce i
| Condition(s) | Cranioplasty, Postoperative Complications, Risk Assessment |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Cranial defects often result from brain injuries, hemorrhages, strokes, or brain tumors. These conditions can increase pressure inside the skull, and if left untreated, may lead to dangerous complications like brain herniation. To manage this, a common procedure called decompressive craniectomy is performed to reduce intracranial pressure. While this surgery often stabilizes the patient's condition, it leaves a cranial defect that exposes the brain to external risks, including pressure fluctuations and potential damage. In severe cases, patients with larger defects may develop complications such as sinking skin flap syndrome. Cranial reconstruction, also known as cranioplasty, is an important procedure to restore the skull's structure and protect the brain. This surgery can improve brain f |
| Who can participate | Inclusion Criteria: * Patients who underwent cranioplasty in the Department of Neurosurgery at Qilu Hospital of Shandong University, Tangdu Hospital of Air Force Medical University, or Daping Hospital, Army Military Medical University between January 1, 2015, and July 31, 2023 * Diagnosed with cranial defects * Possessed complete and accessible electronic medical records * Patients had no prior history of cranioplasty Exclusion Criteria: * Patients with a prior history of cranioplasty * Severe comorbidities (such as serious cardiac, liver, kidney and immune system dysfunction) * Congenital cranial defects * Severe missing data |
| Sex | All |
| Lead sponsor | Qilu Hospital of Shandong University |
| Locations | Chongqing, Chongqing Municipality, China; Xi'an, Shaanxi, China; Jinan, Shandong, China |
| Start date | 2024-12-17 |
| NCT ID | NCT06740773 |
| Official listing | https://clinicaltrials.gov/study/NCT06740773 |