Royal Jelly as a Strategy to Modulate Inflammation and Oxidative Stress in Patients With S
The study aims to evaluate the effect of the royal jelly on inflammation and oxidative stress in participants with systemic arterial hypertension. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants for two months.
| Condition(s) | Hypertension, Cardiovascular Diseases (CVD), Inflammation |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The study aims to evaluate the effect of the royal jelly on inflammation and oxidative stress in participants with systemic arterial hypertension. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants for two months. |
| Who can participate | Inclusion Criteria: * Diagnosis of stage 1 hypertension * Regular treatment for more than 6 months * No changes in medication doses during the last 3 months Exclusion Criteria: * Autoimmune diseases * Infectious diseases * Diabetes * Chronic kidney disease * Liver disease * Cancer * AIDS * Pregnant women * Use of catabolic drugs or antibiotics * Use of antioxidant vitamin supplements, prebiotics, probiotics, or synbiotics * Habitual intake of royal jelly * Allergy to bee stings * Acute myocardial infarction (AMI) * Stroke (CVA) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Lead sponsor | Universidade Federal Fluminense |
| Locations | Rio de Janeiro, Rio de Janeiro, Brazil |
| Start date | 2024-09-18 |
| NCT ID | NCT06917131 |
| Official listing | https://clinicaltrials.gov/study/NCT06917131 |