Sickle Cell, Pain and Mediterranean Diet
The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet.
| Condition(s) | Sickle Cell, Sickle Cell Disease, Sickle Cell Disease Without Crisis, Mediterranean Diet |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet. |
| Who can participate | Inclusion Criteria: * Sickle Cell Disease Diagnosis * Chronic non-vaso-occlusive pain experienced on average ≥ 3 days per week for \> 6 months (based on a response of "Most days," "Every day," or "Some days" and not "Never" to the question "In the past 6 months, how often have you had pain?") * Ability to speak, read, write, and understand English * A Mediterranean Eating Pattern for Americans (MEPA-III) score \<13, indicating that they do not follow a Mediterranean diet. Exclusion Criteria: * Having taken systemic antimicrobials (to treat an infection in the previous 4 weeks) * History of colon cancer or inflammatory bowel disease (given potential untoward effects on the gut microbiome) * History of Clostridium difficile infection in the preceding 12 weeks; (4) unable to agree to maintain |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | University of Illinois at Chicago |
| Locations | Chicago, Illinois, United States |
| Start date | 2025-05-01 |
| NCT ID | NCT06886477 |
| Official listing | https://clinicaltrials.gov/study/NCT06886477 |