Speech Pattern Evaluation and Analysis for Knowledge of AD
The goal of this observational study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer's disease and related dementias (ADRD). This study aims to clarify how speech may be affected by Alzheimer's disease. Participants will complete speech collection sessions and a
| Condition(s) | Wisconsin Alzheimer's Disease Research Center, Wisconsin Registry for Alzheimer's Prevention |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The goal of this observational study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer's disease and related dementias (ADRD). This study aims to clarify how speech may be affected by Alzheimer's disease. Participants will complete speech collection sessions and a survey at home using an iPad. Participants can expect to be in the study for 3 years. |
| Who can participate | Inclusion Criteria: * Must be enrolled in the Wisconsin Alzheimer's Disease Research Center (W-ADRC) Clinical Core or IMPACT studies, or in the Wisconsin Registry for Alzheimer's Prevention (WRAP) * Cognitively unimpaired or have a diagnosis of Mild Cognitive Impairment (MCI) * Ages 40-80 years * Completion of a W-ADRC or WRAP study visit within the past or upcoming 12 months * Have provided W-ADRC or WRAP with blood plasma Alzheimer's Disease Exclusion Criteria: * Not actively enrolled in W-ADRC or WRAP * Diagnosis of dementia * Impaired capacity or unwilling to consent * Major neurological conditions * Speech disorders |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of Wisconsin, Madison |
| Locations | Madison, Wisconsin, United States |
| Start date | 2025-01-22 |
| NCT ID | NCT06230783 |
| Official listing | https://clinicaltrials.gov/study/NCT06230783 |