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Stimulation of the Larynx to Treat Unexplained Chronic Cough

Researchers will test the effect of non-invasive vibrotactile stimulation of the larynx on symptom severity of unexplained chronic cough.

Condition(s)Cough
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryResearchers will test the effect of non-invasive vibrotactile stimulation of the larynx on symptom severity of unexplained chronic cough.
Who can participateInclusion Criteria: * Adults aged 18-88 * \>8 weeks of cough * Cough visual analogue scale (VAS): Rating of 30 or greater on a 0-100 cough severity scale * Ability to provide informed consent and independently complete questionnaires * Ability to read and speak English Exclusion Criteria: * Electronic implants (e.g., pacemaker) * Currently doing speech therapy for cough * Contraindications to safe or effective VTS device use * No regular access to wifi internet Neuromuscular impairment that may affect cough/laryngeal sensation and/or function (e.g., multiple system atrophy, Parkinson, CVA, vocal fold paralysis or paresis) * Untreated carotid disease * BMI \> 40 (for transmission of VTS through soft tissue) * Current or recent (quit \< 3 months ago) smoking * Known currently infectious caus
Ages18 Years to 88 Years
SexAll
Lead sponsorUniversity of Minnesota
LocationsMinneapolis, Minnesota, United States
Start date2021-07-13
NCT IDNCT05273190
Official listinghttps://clinicaltrials.gov/study/NCT05273190

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