Strength Training and Resveratrol
The main goal of this study is to find out if supplementing with resveratrol improves skeletal muscle adaptations to strengthening exercise (resistance training or strength training) in adults age 60+, and to determine whether circulating vehicles of inter-organ communication (extracellular vesicles) and their cargo mi
| Condition(s) | Sarcopenia, Anabolic Resistance |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The main goal of this study is to find out if supplementing with resveratrol improves skeletal muscle adaptations to strengthening exercise (resistance training or strength training) in adults age 60+, and to determine whether circulating vehicles of inter-organ communication (extracellular vesicles) and their cargo might help explain those responses. The investigators will also examine whether resveratrol supplementation improves blood vessel function and cognitive function (brain health) in response to strength training. |
| Who can participate | Inclusion Criteria: * Age 60+ * Minimally active (less than 1 hour of structured exercise/week other than walking) * No resistance training for the previous 6 months * Not currently taking resveratrol supplements * Stable medication, supplement, dietary, and physical activity regimens for the previous 3 months and no plans to change throughout the study period * Body mass at least 110 lbs Exclusion Criteria: * Medical complications that could increase risk during exercise (e.g., cardiovascular disease, uncontrolled hypertension, type 1 or 2 diabetes, orthopedic contraindication to exercise, kidney disease, etc.) * Cannabis or nicotine use * Consume more than 7 alcohol-containing beverages per week |
| Ages | 60 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Texas Tech University |
| Locations | Lubbock, Texas, United States |
| Start date | 2025-06-13 |
| NCT ID | NCT06585865 |
| Official listing | https://clinicaltrials.gov/study/NCT06585865 |