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Strengthening Informed Consent for Authentic Participation in Perinatal HIV Research

This study evaluates a visual Informed Consent Form (ICF) compared to a standard, text-only ICF as an approach to achieving meaningful consent into a clinical trial. The visual ICF uses cartoon characters, graphics and easy-to-understand text to cover the full content of a standard, text-only ICF. In this study, women

Condition(s)Consent Form
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryThis study evaluates a visual Informed Consent Form (ICF) compared to a standard, text-only ICF as an approach to achieving meaningful consent into a clinical trial. The visual ICF uses cartoon characters, graphics and easy-to-understand text to cover the full content of a standard, text-only ICF. In this study, women who are considering enrollment into a clinical trial of a nutrition intervention for their infants will be randomized to either the visual ICF or to the text-only ICF. Qualitative and quantitative data will be collected immediately after the consent process and 8 weeks later. In addition, women not eligible for enrollment into the infant nutrition trial will be asked questions about their opinions regarding the visual ICF. The overall goal of the sub-study is to inform effort
Who can participateInclusion Criteria: * Women ages 18-45 years of age * Pregnant women or women that have recently given birth within the past 2-6 weeks Exclusion Criteria: * Unwilling to provide consent * Severe maternal or infant illness (e.g. tuberculosis, major psychiatric or neurological conditions) * Inability to communicate in one of the three languages (English, isiXhosa, or Afrikaans)
Ages18 Years to 45 Years
SexFemale
Accepts healthy volunteersYes
Lead sponsorColumbia University
LocationsWorcester, Western Cape, South Africa
Start date2024-09-02
NCT IDNCT07122960
Official listinghttps://clinicaltrials.gov/study/NCT07122960

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