Stress and Congestive Heart Failure
The purpose of this study is to investigate whether acute stress can precipitate congestive heart failure (CHF) exacerbation in patients with CHF.
| Condition(s) | Congestive Heart Failure |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The purpose of this study is to investigate whether acute stress can precipitate congestive heart failure (CHF) exacerbation in patients with CHF. |
| Who can participate | Inclusion Criteria: -Heart failure patients over 18 who have or will be receiving a Cardiomems implanted PAP monitor. Exclusion Criteria: * Patients who are unable to perform EMA or laboratory assessments due to cognitive, visual, language, or other disabilities will be excluded. * Patients with Class IV heart failure will also be excluded, as they are already maximally decompensated, and a ceiling/floor effect would preclude effects of stress. * Patients with conditions other than heart failure that affect PA pressures (e.g. dialysis). * Patients with physical conditions that interfere with study participation. * Patients non-compliant with their PAP monitoring. * Patients with chronic opioid use will be excluded. |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Yale University |
| Locations | Hartford, Connecticut, United States; New Haven, Connecticut, United States |
| Start date | 2020-12-02 |
| NCT ID | NCT04551560 |
| Official listing | https://clinicaltrials.gov/study/NCT04551560 |