Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy (fNIRS) in patients with hemiparesis after stroke. Participants in the study performed a simpl
| Condition(s) | Stroke, Stroke with Hemiparesis, Stroke, Ischemic |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy (fNIRS) in patients with hemiparesis after stroke. Participants in the study performed a simple stimulus-response task several times with one healthy and one paralyzed limb at different stages of basic rehabilitation. A group of healthy, age-matched volunteers participated in the same experiment to verify the stroke-related changes. The researchers recorded fNIRS signals, muscle activity using electromyography, and heart activity using electrocardiography. |
| Who can participate | For Healthy Volunteers: Inclusion Criteria: 1\. Availability of signed written informed consent. 3. Absence of somatic and psychiatric diseases (more details in the exclusion criteria) 4. Ability and willingness to comply with the requirements of this protocol. Exclusion Criteria: 1. The presence of superficial injury of head (S00-S09 International Classification of Diseases 10 (ICD-10). 2. The presence of mental, behavioural disorders (F00-F99 ICD-10). 3. Drug addiction in the past or at the moment. 4. The presence of diseases of the nervous system (G00-G99 ICD-10). 5. . History of intracranial injury (S06 ICD-10) or stroke (I64 ICD-10). 6. The presence of somatoform disorders (F45 ICD-10). 7. Any conditions that, in the opinion of the Investigator, meet the exclusion criteria 8. Presence |
| Ages | 35 Years to 70 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Skolkovo Institute of Science and Technology |
| Locations | Moscow, Russia; Moscow, Russia |
| Start date | 2024-06-26 |
| NCT ID | NCT06806397 |
| Official listing | https://clinicaltrials.gov/study/NCT06806397 |