Study on the Diagnosis and Management of CLL in Italy by GIMEMA
retrospective and prospective multicenter observational clinical and biological data collection from all patients with newly diagnosed CLL, SLL or MBL. retrospective cohort: all cases with a diagnosis between January 1st 2010 and August 31th 2021. prospective cohort: all patients with a diagnosis between September 1st
| Condition(s) | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, MBL-CLL - Monoclonal B-Cell Lymphocytosis Chronic Lymphocytic Leukaemia-Type |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | retrospective and prospective multicenter observational clinical and biological data collection from all patients with newly diagnosed CLL, SLL or MBL. retrospective cohort: all cases with a diagnosis between January 1st 2010 and August 31th 2021. prospective cohort: all patients with a diagnosis between September 1st 2021 and September 1st 2025. |
| Who can participate | Inclusion Criteria: 1. Age ≥18 years at diagnosis 2. One of the following diagnoses that meet the international diagnostic criteria (iwCLL2018 and WHO2017) 1. Chronic lymphocytic leukemia (CLL) 2. Small lymphocytic lymphoma (SLL) 3. CLL-like monoclonal B-cell lymphocytosis (MBL) 3. Retrospective cohort: CLL/SLL/MBL diagnosis between January 1st 2010 and August 31th 2021. 4. Prospective cohort: CLL/SLL/MBL diagnosis between September 1st 2021 and September 1st, 2025. 5. Signed written informed consent according to ICH/EU/GCP and national local laws (if applicable) Exclusion Criteria: * \- - |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Gruppo Italiano Malattie EMatologiche dell'Adulto |
| Locations | Alessandria, Italy; Brescia, Italy; Brindisi, Italy; Candiolo, Italy; Florence, Italy; Messina, Italy (+18 more sites) |
| Start date | 2021-10-13 |
| NCT ID | NCT04867915 |
| Official listing | https://clinicaltrials.gov/study/NCT04867915 |