Supportive-Expressive and Emotion-Focused Treatment for Depression
This study will explore the mechanisms of change that are activated when individuals receive a treatment that targets their weakness and the mechanisms activated when the treatment capitalize on their strength. Patients will be assigned to one of two types of psychotherapies in treating people with a major depression d
| Condition(s) | Major Depressive Disorder |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This study will explore the mechanisms of change that are activated when individuals receive a treatment that targets their weakness and the mechanisms activated when the treatment capitalize on their strength. Patients will be assigned to one of two types of psychotherapies in treating people with a major depression disorder, expressive-supportive vs. emotion-focused treatment. Their ability to benefit from treatment based on their pre-treatment levels of insight and emotional processing will be examined. This is a four-month protocol, with a 2 year follow up period. |
| Who can participate | Inclusion Criteria: * Meeting major depressive disorder diagnostic criteria using the structured clinical interviews for Diagnostic and Statistical Manual of Mental Disorders-5 and scoring more than 14 on the 17-item Hamilton rating scale for depression at two evaluations (one week apart) (Hamilton, 1967). * If on medication, patients' dosage must be stable for at least three months prior to entering the study, and they must be willing to maintain stable dosage for the duration of treatment * Age between 18 and 65 * Hebrew language fluency * Provision of written informed consent. Exclusion Criteria: * Current risk of suicide or self-harm * current substance abuse disorders * current or past schizophrenia or psychosis, bipolar disorder, or severe eating disorder requiring medical monitoring |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Lead sponsor | University of Haifa |
| Locations | Haifa, Israel |
| Start date | 2020-11-29 |
| NCT ID | NCT04576182 |
| Official listing | https://clinicaltrials.gov/study/NCT04576182 |