Surviving the Pediatric Intensive Care Unit (PICU)
Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness. However, PICU survivors are at risk of long-term health sequalae. Given the increased recognition of physical, cognitive, and psychological sequelae in P
| Condition(s) | Post Intensive Care Syndrome (PICS) |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness. However, PICU survivors are at risk of long-term health sequalae. Given the increased recognition of physical, cognitive, and psychological sequelae in PICU survivors, the concept of post-intensive care syndrome-pediatrics (PICS-p) has been proposed. Besides the PICU patient/survivor, the PICS-p framework also highlights the impacts of a child's critical illness has on the family. The impact of a PICU admission extends beyond the patient and parents, potentially affecting healthy siblings who are navigating their own developmental challenges. Healthy siblings may face emotional distress, increased responsibilities, and disrup |
| Who can participate | Inclusion Criteria: \[HOPE Cohort\] 1. Between 28 days - 16 years of age at PICU admission 2. Have an expected PICU stay \> 48 hours\* \[SHACK-S Cohort\] 1. Healthy children (aged 4 -16 years old) with critically ill sibling between 28 days - 16 years of age at PICU admission 2. Has a critically ill sibling who has an expected PICU stay \> 48 hours 3. Lives in the same household as the critically ill sibling and parents prior to admission Exclusion Criteria: \[HOPE Cohort\] 1. Do-Not-Resuscitate status 2. Lack of informed consent 3. Prior enrolment in this study \[SHACK-S Cohort\] 1. Children of critically ill sibling with Do-Not-Resuscitate status 2. Children with condition listed on paediatric Complex Chronic Conditions (CCC) system Version 3.0 or with neurocognitive/neurodevelopmental d |
| Ages | 28 Days to 16 Years |
| Sex | All |
| Lead sponsor | KK Women's and Children's Hospital |
| Locations | Singapore, Singapore, Singapore; Singapore, Singapore, Singapore |
| Start date | 2025-02-11 |
| NCT ID | NCT06812130 |
| Official listing | https://clinicaltrials.gov/study/NCT06812130 |