The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During
Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during anesthesia induction and to explore its guiding significance for anesthesia management. The goa
| Condition(s) | Airway Management, Induction of Anesthesia |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during anesthesia induction and to explore its guiding significance for anesthesia management. The goal is to provide a more precise and personalized ventilation pressure setting standard for clinical anesthesia, thereby enhancing the safety of the anesthesia induction phase. |
| Who can participate | Inclusion Criteria: 1. Age: 18-65 years, regardless of gender; 2. ASA classification: I-III; 3. Scheduled for elective general anesthesia surgery; 4. BMI: 18.0-28.0 kg/m²; 5. Preoperative fasting: Solid food \>6 hours, liquid \>2 hours; 6. Less than two from five criteria predicting difficult mask ventilation as described by Langeron et al.(Prediction of difficult mask ventilation. Anesthesiology 2000; 92:1229-36); 7. No severe underlying conditions such as heart, lung, liver, or kidney disease; 8. Signed informed consent and ability to cooperate with the study protocol. Exclusion Criteria: 1. Pregnant or breastfeeding women; 2. History of upper gastrointestinal diseases such as gastroesophageal reflux disease, peptic ulcers, or hiatal hernia; 3. Recent (within 2 weeks) respiratory infecti |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Lead sponsor | Affiliated Hospital of Jiaxing University |
| Locations | Jiaxing, China |
| Start date | 2025-09-29 |
| NCT ID | NCT07340255 |
| Official listing | https://clinicaltrials.gov/study/NCT07340255 |