The Combined Use of PRP with Lipoaspirate And/or Bone Marrow Aspirate in Osteoarthritis
To demonstrate the efficacy of the combined use of platelet-rich plasma (PRP) with lipoaspirate and/or bone marrow aspirate in osteoarthritis of major joints, and to compare the outcomes achieved using three combinations: PRP plus lipoaspirate, PRP plus bone marrow aspirate, and PRP plus both lipoaspirate and bone marr
| Condition(s) | Osteoarthritis |
|---|---|
| Status | Recruiting |
| Phase | Phase 2 |
| Study type | Interventional |
| Summary | To demonstrate the efficacy of the combined use of platelet-rich plasma (PRP) with lipoaspirate and/or bone marrow aspirate in osteoarthritis of major joints, and to compare the outcomes achieved using three combinations: PRP plus lipoaspirate, PRP plus bone marrow aspirate, and PRP plus both lipoaspirate and bone marrow aspirate. |
| Who can participate | Inclusion Criteria: 1. Capable of providing written informed consent and willing and able to adhere to all protocol requirements. 2. Male or female at least 19 years of age at the time of providing written informed consent. 3. Evidence of OsteoArthritis in a major joint requires recent (within one year) imaging, either by x-ray or MRI. Kellgren \& Lawrence Grades 1-3 are accepted for participation. Exclusion Criteria: 1. BMI \> 35 2. Arthroscopic surgery to the treatment joint within 12 months 3. Cortisone or HA injection within the last 3 months prior to stem cell injection 4. Inability to hold antiplatelet therapy according to treating provider prior to procedure 5. Kellgren \& Lawrence Grade 4 Osteoarthritis 6. Participants with a platelet count less than 100 x 109 7. Participants with |
| Ages | 19 Years to 79 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Dr. Grant M. Pagdin |
| Locations | Kelowna, British Columbia, Canada |
| Start date | 2020-09-01 |
| NCT ID | NCT03984461 |
| Official listing | https://clinicaltrials.gov/study/NCT03984461 |