The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study
Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment e
| Condition(s) | Rheumatoid Arthritis (RA, Atherosclerotic Cardiovascular Disease (ASCVD) |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier. |
| Who can participate | Inclusion Criteria: * RA diagnosed by a rheumatologist * Age 40- 79 * ≥1 ASCVD risk factor including prediabetes, hypertension, BMI \>30, current or history of cigarette smoking Exclusion Criteria: * Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor * Patients with diabetes mellitus * Pregnancy |
| Ages | 35 Years to 79 Years |
| Sex | All |
| Lead sponsor | Brigham and Women's Hospital |
| Locations | Boston, Massachusetts, United States |
| Start date | 2024-09-04 |
| NCT ID | NCT07315997 |
| Official listing | https://clinicaltrials.gov/study/NCT07315997 |