The Effect of Olfactory Training in Patients With COVID-19 Induced Olfactory Dysfunction
Aim: The aim is to investigate the effect of olfactory training with essential oils versus olfactory training with placebo-oils in patients with COVID-19 induced olfactory dysfunction Study design: The study is a placebo-controlled randomized clinical trial with an intervention group and a control group. The interventi
| Condition(s) | COVID-19 |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Aim: The aim is to investigate the effect of olfactory training with essential oils versus olfactory training with placebo-oils in patients with COVID-19 induced olfactory dysfunction Study design: The study is a placebo-controlled randomized clinical trial with an intervention group and a control group. The intervention group receive four essential oils with scents of orange, lavender, clove, and peppermint. Patients in the control group receive a fragrance kit, consisting of the same containers, but with fragrance-free oils added. Both groups are instructed to smell each of the four oils for 30 seconds in the morning and evening, over a three-month intervention period. Patients are given a diary in which to record their olfactory training. The nurse or medical student instructing the pat |
| Who can participate | Inclusion Criteria: * Olfactory dysfunction caused by COVID-19 * Hyposmia (16.25-30.5) or anosmia (\<16) with or without parosmia assessed by TDI test with Sniffin Sticks performed in the Unit for Sense of Taste and Smell * \> 18 years of age Exclusion Criteria: * Cause of hyposmia, anosmia or parosmia other than COVID-19 * Does not read or speak Danish * Lack of compliance to perform daily olfactory training |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Ditte Gertz Mogensen |
| Locations | Copenhagen, Denmark |
| Start date | 2022-06-29 |
| NCT ID | NCT05539560 |
| Official listing | https://clinicaltrials.gov/study/NCT05539560 |