The Effectiveness of Guided Botulinum Toxin "A" Injection to the Masticatory Muscles in th
The aim of this study, is to evaluate the effectiveness of ultrasound guided injection of botulinum toxin A into the muscles of mastication; the masseter, temporalis and the lateral pterygoid, in a closed reduction approach of condylar and sub-condylar fractures, seeking to shed light on the efficacy and potential adva
| Condition(s) | Condylar Fractures, Subcondylar Fracture |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The aim of this study, is to evaluate the effectiveness of ultrasound guided injection of botulinum toxin A into the muscles of mastication; the masseter, temporalis and the lateral pterygoid, in a closed reduction approach of condylar and sub-condylar fractures, seeking to shed light on the efficacy and potential advantages of this innovative therapeutic avenue. |
| Who can participate | Inclusion Criteria: * Having unilateral extra-capsular condylar/ sub-condylar fractures isolated or associated with other fractures. * Isolated intra-capsular fractures. * Moderate condylar displacement, JO to 45 degrees or incomplete fractures. * Reproducible occlusion without drop-back or with drop-back that returns to midline on release of posterior force. * Availability of more than half of the dentition Exclusion Criteria: * Bilateral condylar fractures * Gross condylar displacement\> 45 degrees (severely displaced) * Anatomic reduction of ramus height 2: 2 mm * Unstable occlusion (e.g., periodontal disease, less than three teeth per quadrant) * Patients with severe polytraumas. * Patients with relative contraindications to BTX injections that may include; pregnancy, lactation, BTX Al |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Lead sponsor | Pakinam Gheeta |
| Locations | Alexandria, Egypt |
| Start date | 2025-04-10 |
| NCT ID | NCT07374341 |
| Official listing | https://clinicaltrials.gov/study/NCT07374341 |