The Effects of Diet on Small Non-coding RNA i Sperm Cells and the Possible Effects on Repr
In this study, patients with infertility treated with IVF at the Center of Reproductive Medicine in Linköping, Sweden, will receive recipes and food according to Nordic dietary guidelines. The purpose is to investigate whether a short diet intervention is sufficient to improve sperm quality and shift the small non-codi
| Condition(s) | Changes in sncRNA in Sperm, Male Fertility, RNA Profile |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | In this study, patients with infertility treated with IVF at the Center of Reproductive Medicine in Linköping, Sweden, will receive recipes and food according to Nordic dietary guidelines. The purpose is to investigate whether a short diet intervention is sufficient to improve sperm quality and shift the small non-coding RNA profile. In our previous study sperm showed rapid response to diet. |
| Who can participate | Inclusion Criteria: * Male (biological) partner in infertile couple, scheduled for first IVF treatment * Mature sperm cells in semen * Able to speak and read Swedish * Omnivore * Will refrain from nicotine and alcohol during intervention * Sperm sampled provided no more than 3 weeks before intervention start Exclusion Criteria: * Former or present malignant disease * Former radiotherapy in pelvic area * Former chemotherapy * Known genetic/chromosomal disorder * Food allergy |
| Ages | 23 Years to 56 Years |
| Sex | Male |
| Lead sponsor | Ostergotland County Council, Sweden |
| Locations | Linköping, Östergötland County, Sweden |
| Start date | 2024-12-26 |
| NCT ID | NCT06831292 |
| Official listing | https://clinicaltrials.gov/study/NCT06831292 |