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The Lung Health Check Pilot

This study aims to test if it is feasible to introduce lung cancer screening in Ireland. People within a certain age group, who smoke or who smoked in the past, are at a greater risk of developing lung cancer. They can also develop chronic lung conditions that can affect their long-term health. In Ireland, about 2,690

Condition(s)Non-Small Cell Lung Cancer
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryThis study aims to test if it is feasible to introduce lung cancer screening in Ireland. People within a certain age group, who smoke or who smoked in the past, are at a greater risk of developing lung cancer. They can also develop chronic lung conditions that can affect their long-term health. In Ireland, about 2,690 people are diagnosed with Lung Cancer every year. Unfortunately, 2 out of every 3 people diagnosed with lung cancer die per year. The goal of this study is to try to screen for lung cancer in people before they have symptoms associated with the disease. We aim to do this by selecting people based on their age, whether they have smoked in the past or currently smoke as well as other relevant factors. People who take part in this study will have an assessment of how their lungs
Who can participateInclusion Criteria: 1. 55 - 74 years of age 2. Current or former smokers * Current: \>100 cigarettes in lifetime and/or currently tobacco smoking * Former: \>100 cigarettes in lifetime and/or no tobacco smoking \>= 28 days 3. Referred from a GP for the LHC pilot 4. PLCOM2012 ≥ 1.51% or LLPv2 ≥2.5% (Lung Cancer Risk Scores) * Prostate Lung Cancer Colorectal Ovarian (PLCO) \& Liverpool Lung Project Version 2 (LLPv2) Exclusion Criteria: 1. Participant-reported history of chest CT in the last 12 months 2. Inability to undergo non-contrast CT (e.g. \>200 kg body weight, inability to lie flat) 3. Participant reported known diagnosis of other advanced stage cancers 4. Participant reported diagnosis of lung cancer of any stage in the last 5 years 5. Likely non-compliance with study procedures, as
Ages55 Years to 74 Years
SexAll
Accepts healthy volunteersYes
Lead sponsorRoyal College of Surgeons, Ireland
LocationsDublin, Ireland
Start date2025-05-19
NCT IDNCT07099027
Official listinghttps://clinicaltrials.gov/study/NCT07099027

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