The Venous Distension Reflex and Orthostatic Hypertension
This research is being done to find out whether distension of veins in legs will cause a rise in blood pressure (orthostatic hypertension).
| Condition(s) | Blood Pressure |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This research is being done to find out whether distension of veins in legs will cause a rise in blood pressure (orthostatic hypertension). |
| Who can participate | Inclusion Criteria: * Are capable of giving informed consent * Are of any race or ethnicity * Are fluent in written and spoken English * Whose history and physical exam did not uncover any exclusion criteria * Are 18 years of age For subjects with elevated standing BP * Systolic BP (SBP) during standing is at least 10 mmHg \> the supine SBP * Patients with a diagnosis of stage I hypertension without other chronic diseases may be INCLUDED For normal subjects without elevated standing BP * The change in SBP by standing is within ± 5 mmHg from the supine SBP * Matched gender, similar age and BMI (within 10%) to participants with elevated standing BP * Free of acute or chronic medical conditions Exclusion Criteria: * Age \< 18 years of age * Are a pregnant or nursing woman * Are a prisoner or |
| Ages | 18 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Milton S. Hershey Medical Center |
| Locations | Hershey, Pennsylvania, United States |
| Start date | 2020-03-10 |
| NCT ID | NCT03496792 |
| Official listing | https://clinicaltrials.gov/study/NCT03496792 |