Timing of Soft Tissue Grafting Following Immediate Implant Placement
Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT). Prior to surgery, a small- field low-dose cone beam computed tomography (CBCT) is taken to verify the integrity of the facial bone wall and an adequate amount of apica
| Condition(s) | Bone Resorption |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT). Prior to surgery, a small- field low-dose cone beam computed tomography (CBCT) is taken to verify the integrity of the facial bone wall and an adequate amount of apical and palatal bone availability for implant anchorage. In all of the patients, a connective tissue graft (CTG) will be harvested and inserted into the buccal mucosa to increase soft tissue thickness around the immediately installed implant. However, included patients will be randomly allocated to either receive the CTG immediately after implant installation (Immediate soft tissue grafting, ISG = control group) or 3 months after implant installation (Delayed soft tissue grafti |
| Who can participate | Inclusion Criteria: * At least 20 years old * Good oral hygiene defined as full-mouth plaque score ≤ 25% (O'Leary et al. 1972) * Presence of an incisor, cuspid or premolar in the maxilla that needs to be extracted for any reason with at least one neighboring tooth present * At least 3 mm bone available at the apical or palatal aspect of the alveolus as assessed on CBCT to ensure primary implant stability * Intact buccal bone wall at the time of extraction * Written informed consent Exclusion Criteria: * Pregnancy * Systemic diseases * Smoking * Suppuration * \> 1 mm gingival asymmetry between the failing and contralateral tooth * Untreated periodontal disease; untreated caries lesions |
| Ages | 20 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University Ghent |
| Locations | Ghent, Oost-Vlaanderen, Belgium |
| Start date | 2022-08-01 |
| NCT ID | NCT05537545 |
| Official listing | https://clinicaltrials.gov/study/NCT05537545 |