Tissue Engineered Cartilage to Repairing Articular Cartilage Defects
The joint cartilage constructed by combining bone marrow mesenchymal stem cells with three-dimensional materials has achieved the goal of repairing joint cartilage.
| Condition(s) | Cartilage Injury, OA Knee |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The joint cartilage constructed by combining bone marrow mesenchymal stem cells with three-dimensional materials has achieved the goal of repairing joint cartilage. |
| Who can participate | Inclusion Criteria: 1. The patients' age ranges from 18 to 65 years old, and gender is not restricted; 2. The imaging results show that the epiphyseal growth is mature; 3. The defects or localized injuries of joint cartilage caused by trauma or other reasons; 4. The injured area is the distal weight-bearing surface of the femoral condyle of the knee joint, with no more than 4 lesions, and there is no injury to the cruciate ligaments; 5. The patients voluntarily sign and provide a written informed consent form and are willing to closely cooperate with the doctor's strict postoperative rehabilitation program. Exclusion Criteria: 1. The patient is extremely overweight, with a body mass index greater than 35; 2. The lower limb alignment is valgus by more than 10° and varus by more than 5°; 3. |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Lead sponsor | The First Affiliated Hospital of Xinxiang Medical College |
| Locations | Xinxiang, Henan, China |
| Start date | 2026-04-20 |
| NCT ID | NCT07094100 |
| Official listing | https://clinicaltrials.gov/study/NCT07094100 |