Top-Down Attentional Control of Visual-Processing
Background: \- Previous studies have shown that people with certain types of brain damage may have particular problems paying attention and processing things that they see. Researchers are interested in comparing how people with brain damage and without brain damage process visual images. Objectives: \- To better under
| Condition(s) | Focal Brain Lesion, Focal Lesions, fMRI |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Background: \- Previous studies have shown that people with certain types of brain damage may have particular problems paying attention and processing things that they see. Researchers are interested in comparing how people with brain damage and without brain damage process visual images. Objectives: \- To better understand the areas of the brain involved in paying attention to things that are seen. Eligibility: \- Individuals at least 18 years of age who either have had damage to one or both sides of specific parts of the brain (e.g., stroke, injury, certain neurosurgery procedures) or are healthy volunteers. Design: * The study involves 4 to 10 visits to the NIH Clinical Center over 1 to 2 years. Each visit will last approximately 2 hours. * Participants will be screened with a medical h |
| Who can participate | * INCLUSION CRITERIA: All Subjects 1. All subjects will be 18 years of age or older and have at least a high school education. 2. Capacity to provide their own informed consent, understand and cooperate with study procedures. 3. Able to read and write in English to guarantee understanding of all written and spoken instructions, which are in English. Patients: 1. Unilateral or bilateral focal lesions of prefrontal, parietal, occipital or temporal cortex, or amygdala. 2. At least three months post-stroke, lobectomy and or neurosurgical resection. Healthy volunteers: 1\. Neurologically normal and in good general health. EXCLUSION CRITERIA Patients: 1. Any neurological or psychiatric disorder not related to the focal lesion (e.g., epilepsy, schizophrenia, etc.). Epilepsy patients who have unde |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | National Institute of Mental Health (NIMH) |
| Locations | Bethesda, Maryland, United States |
| Start date | 2012-07-23 |
| NCT ID | NCT01087281 |
| Official listing | https://clinicaltrials.gov/study/NCT01087281 |