Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer
This study aims to compare the efficacy of fluoroscopy-guided paravertebral (PV) and transdiscal (TD) approaches for splanchnic nerve neurolysis in patients with upper abdominal cancer-related pain (e.g., gastric, pancreatic, and hepatic malignancies). Treatment response will be assessed using the Numerical Rating Scal
| Condition(s) | Cancer Pain |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This study aims to compare the efficacy of fluoroscopy-guided paravertebral (PV) and transdiscal (TD) approaches for splanchnic nerve neurolysis in patients with upper abdominal cancer-related pain (e.g., gastric, pancreatic, and hepatic malignancies). Treatment response will be assessed using the Numerical Rating Scale (NRS), and the impact of both techniques on quality of life will be evaluated with the EORTC QLQ-C30 questionnaire. |
| Who can participate | Inclusion Criteria: * Severe abdominal pain (NRS \> 6) due to upper intra-abdominal organ malignancies (such as gastric, pancreatic, or hepatic cancer). * Failure of pain control with conservative treatment modalities. Exclusion Criteria: * Presence of local anatomical variations * Localized or systemic infection involving the procedural site * Pregnancy * Coagulopathy * Presence of unstable psychiatric disorders |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Ankara Etlik City Hospital |
| Locations | Ankara, Turkey (Türkiye) |
| Start date | 2026-02-16 |
| NCT ID | NCT07445386 |
| Official listing | https://clinicaltrials.gov/study/NCT07445386 |