Trilateral Retinoblastoma: Incidence and Outcomes
Patients with heritable retinoblastoma are at risk to develop an intracranial brain tumor, which is often fatal. The investigators intend to look at the incidence and survival of trilateral retinoblastoma (which is a brain tumor that can either be located in the pineal gland or elsewhere in the brain) in retinoblastoma
| Condition(s) | Trilateral Retinoblastoma, Retinoblastoma |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Patients with heritable retinoblastoma are at risk to develop an intracranial brain tumor, which is often fatal. The investigators intend to look at the incidence and survival of trilateral retinoblastoma (which is a brain tumor that can either be located in the pineal gland or elsewhere in the brain) in retinoblastoma patients globally. All retinoblastoma patients from participating centers will be included. The investigators hypothesize that the apparent incidence of trilateral retinoblastoma (especially the usually later diagnosed pineal trilateral retinoblastoma) in low-income countries will be lower because of low chances of surviving the ocular tumors at about 50% and also because of possible under-diagnosis. Therefore, as retinoblastoma care improves in low-income countries the inci |
| Who can participate | Inclusion Criteria: * patients diagnosed with retinoblastoma Exclusion Criteria: * none |
| Sex | All |
| Lead sponsor | Amsterdam UMC, location VUmc |
| Locations | Amsterdam, North Holland, Netherlands |
| Start date | 2024-01-01 |
| NCT ID | NCT06367530 |
| Official listing | https://clinicaltrials.gov/study/NCT06367530 |