Type 1 Diabetes and Obstructive Sleep Apnea
The purpose of the study is to investigate the role of sleep apnea in glycemic dysregulation in adults with Type 1 diabetes.
| Condition(s) | Sleep Apnea, Obstructive, Type 1 Diabetes (T1D) |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The purpose of the study is to investigate the role of sleep apnea in glycemic dysregulation in adults with Type 1 diabetes. |
| Who can participate | Inclusion Criteria: * Age: 18 to 50 years old * Type 1 Diabetes on insulin pump therapy and using a CGM device with an GMI (glucose management indicator) between 5.5 and 8.5% with hemoglobin in the normal range at screening * OSA by home sleep apnea test Exclusion Criteria: * Regular and adherent CPAP use per clinical guidelines * Requiring oxygen or advanced positive airway pressure modalities during sleep * Having a 'fall-asleep' or 'near miss' accident in the past 6-months * Shift work * Severe hypoglycemia (≥1 episode in the past 3 months or diagnosis of hypoglycemic unawareness) * ≥1 trip to emergency room for poor glucose management in the past 6 months * Proliferative retinopathy * Fasting triglycerides \>400mg/dL, * Liver transaminases \>2 times upper limit of normal, * Renal trans |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Lead sponsor | University of Chicago |
| Locations | Chicago, Illinois, United States |
| Start date | 2025-11-10 |
| NCT ID | NCT06915831 |
| Official listing | https://clinicaltrials.gov/study/NCT06915831 |