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UK Imaging Diabetes Study Seeing Diabetes Clearly

Prospective, observational cohort study to cross-sectionally assess the health of multiple organs, using multiparametric abdominal magnetic resonance imaging (MRI) scan, and understand if resulting MRI metrics can predict future clinical events over a period of 5 years, in adult patients with type 2 diabetes lacking hi

Condition(s)Type2 Diabetes
StatusRecruiting
Study typeObservational
SummaryProspective, observational cohort study to cross-sectionally assess the health of multiple organs, using multiparametric abdominal magnetic resonance imaging (MRI) scan, and understand if resulting MRI metrics can predict future clinical events over a period of 5 years, in adult patients with type 2 diabetes lacking history of cardiovascular disease.
Who can participateInclusion Criteria: * Male or female at least 18 years of age and diagnosed with type 2 diabetes, with or without diabetic retinopathy. * Participant willing and able to give informed consent for participation in the study. Exclusion Criteria: In 12 months prior to consent, evidence of existing cardiovascular event defined as at least one of: * myocardial infarction * ischaemic stroke * hospital admission/discharge for unstable angina * heart surgery * unstable angina * transient ischemic attack * The participant may not enter the study if they have any contraindication to magnetic resonance imaging (standard MR exclusion criteria including pregnancy, extensive tattoos, pacemaker, shrapnel injury, severe claustrophobia). * Patients with known autoimmune hepatitis, viral hepatitis, Wilson's
Ages18 Years
SexAll
Lead sponsorPerspectum
LocationsDidcot, Oxfordshire, United Kingdom; Eynsham, Oxfordshire, United Kingdom; Farringdon, Oxfordshire, United Kingdom; Witney, Oxfordshire, United Kingdom; Redhill, Surrey, United Kingdom; Baglan, Swansea, United Kingdom (+6 more sites)
Start date2022-05-30
NCT IDNCT05057403
Official listinghttps://clinicaltrials.gov/study/NCT05057403

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