Validation of Energy Expenditure Measures Study
The energy that the human body burns and the amount of food consumed determine a person's body weight. If food intake covers the amount of energy burned, body weight remains constant - a state known as energy balance. Achieving an energy balance is not easy in everyday life. This is reflected in the increasing number o
| Condition(s) | Obesity Prevention, Healthy |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The energy that the human body burns and the amount of food consumed determine a person's body weight. If food intake covers the amount of energy burned, body weight remains constant - a state known as energy balance. Achieving an energy balance is not easy in everyday life. This is reflected in the increasing number of people suffering from morbid obesity. To counteract this development, it is important to have a better understanding of how much food a person should eat. In this study, the investigators will investigate the amount of food needed to meet a person's energy needs and bring them into energy balance. Primary aims of the study are i) to technically and biologically validate two whole-room indirect calorimeters (WRICs) and ii) by using whole-room indirect calorimetry, to achieve |
| Who can participate | Inclusion Criteria: * Abilty to provide informed consent * Written declaration of consent * Healthy study participants * Able to perform moderate physical exercise using a bike ergometer * Women: continuous contraception/fullicular phase of menstrual cycle Exclusion Criteria: * Weight change \> 5 kg or 5% of body weight in the last 3 months * Nicotine abuse, Alcohol/drug abuse * Strenuous physical activity in everyday life \> 1 h per day * Body mass index \< 18.5 kg/m² or ≥ 40 kg/m² * Chronic diseases with an impact on energy expenditure * Food allergy/intolerance, vegan diet * Circumstances that speak against the application of wearable accelerometers (e.g. silicone contact allergy) * Impaired fasting glucose, diabetes mellitus and prediabetes * Pregnancy/breastfeeding * Claustrophobia * |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Lead sponsor | University of Leipzig |
| Locations | Leipzig, Saxony, Germany |
| Start date | 2025-08-26 |
| NCT ID | NCT07155564 |
| Official listing | https://clinicaltrials.gov/study/NCT07155564 |