Venous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensa
The purpose of this study is to assess the feasibility, safety and effectiveness of VExUS guided organ decongestion compared to standard of care in patients hospitalized with acute decompensated heart failue (ADHF). 180 patients will be randomly assigned to either intervention (VExUS) arm or standard of care (SOC) arm.
| Condition(s) | Cardiorenal Syndrome, Heart Failure, Acute Kidney Injury, Acute Decompensated Heart Failure |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The purpose of this study is to assess the feasibility, safety and effectiveness of VExUS guided organ decongestion compared to standard of care in patients hospitalized with acute decompensated heart failue (ADHF). 180 patients will be randomly assigned to either intervention (VExUS) arm or standard of care (SOC) arm. In the intervention arm, the treatment team will be informed by the study team about the results of the VExUS examination to supplement the clinical decision of proper decongestion treatment, while no information will be provided in the standard of care arm. Study visits are scheduled every second day while hospitalized, end of study is set to day of discharge from the ward. Telephone consultation and review of medical journal scheduled after 6 months to assess exploratory e |
| Who can participate | Inclusion Criteria: * 18 years of age or above * Admitted the ward of Department of Cardiology OUH Ullevål with a clinical diagnosis of ADHFdefined by European Society of Cardiology * Pro-BNP \> 800 ng/l at first day of admission * Capable of giving signed informed consent Exclusion Criteria: \- Any medical or psychiatric condition which in the opinion of the investigatorprecludes participation |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Oslo University Hospital |
| Locations | Oslo, Norway |
| Start date | 2024-09-16 |
| NCT ID | NCT06714409 |
| Official listing | https://clinicaltrials.gov/study/NCT06714409 |