Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who have undergone anterior cruciate ligament reconstruction surgery (ACLR). The main objectives a
| Condition(s) | Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who have undergone anterior cruciate ligament reconstruction surgery (ACLR). The main objectives are to compare the effects of Standard rehabilitation vs. rehabilitation that includes whole body vibration (WBV) or local muscle vibration (LMV) on: * Quadriceps muscle function * Gait biomechanics linked to post-traumatic knee osteoarthritis development * Patient self-report outcomes * MRI indicators of knee joint health and muscle quality * Landing biomechanics linked to secondary ACL injury risk * Evidence-based return-to-physical-activity criteria Participants will be ass |
| Who can participate | Inclusion Criteria: * Age 16 to 35 years * Unilateral, primary ACLR with bone-patellar tendon-bone autograft Exclusion Criteria: * History of prior ACL injury or revision ACLR * History of prior knee surgery * Requirement of multiple ligament surgery at time of ACLR * Concomitant injuries or surgical procedures at the time of ACLR that would delay early post-operative weight bearing based on surgeon recommendations (e.g. lower extremity fracture, intra-articular fracture, microfracture procedure) * Removal of more than 1/3 of the medial or lateral meniscus at the time of ACLR * Articular cartilage damage greater than 3A on the International Cartilage Repair Society Criteria at the time of ACLR * History of musculoskeletal injury to either leg in the 3 months prior to participation other th |
| Ages | 16 Years to 35 Years |
| Sex | All |
| Lead sponsor | University of North Carolina, Chapel Hill |
| Locations | Chapel Hill, North Carolina, United States; Chapel Hill, North Carolina, United States |
| Start date | 2021-01-11 |
| NCT ID | NCT04875052 |
| Official listing | https://clinicaltrials.gov/study/NCT04875052 |