Vision Loss Impact on Navigation in Virtual Reality
The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavio
| Condition(s) | Stroke, Ischemic, Quadrantanopia, Hemianopsia, Homonymous, Hemianopia, Homonymous, Hemianopia, Hemianopsia, Occipital Lobe Infarct, Visual Field Defect, Peripheral, Vision Loss Partial, Quadrantanopsi |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments. Through the combined use of computer vision, deep learning, and gaze-contingent manipulations of the visual field, this work will test the central hypothesis that changes to visually guided steering behaviors in CB are a consequence of changes to the visual sampling and processing of task-related motion information (i.e., optic flow). |
| Who can participate | Cortically Blind Group: Inclusion Criteria: * Residents of the United States or Canada * Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 75 years (verified by MRI and/or CT scans) * Reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey or equivalent perimetry. * Willing, able, and competent to provide their own informed consent * Cognitively able, responsible to understand written and oral instructions in English * Emmetropic or else wear corrective contact lenses inside the virtual reality headset Exclusion Criteria: * Those who have never driven or earned a drivers' license * Past or present ocular disease interfering with visual acuity * B |
| Ages | 21 Years to 75 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of Rochester |
| Locations | Rochester, New York, United States |
| Start date | 2023-11-28 |
| NCT ID | NCT06047717 |
| Official listing | https://clinicaltrials.gov/study/NCT06047717 |