Wearable Photoplethysmography for Non-invasive Hydration Assessment
Hydration status during exercise is often determined by measuring body mass change, fluid intake and urine output. However, obtaining these measurements can be an invasive, time-consuming process. Hydration status may be detectable by analyzing blood flow patterns of the superficial (just under the skin) blood vessels.
| Condition(s) | Hydration Status |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Hydration status during exercise is often determined by measuring body mass change, fluid intake and urine output. However, obtaining these measurements can be an invasive, time-consuming process. Hydration status may be detectable by analyzing blood flow patterns of the superficial (just under the skin) blood vessels. Wearable devices are now abundant among the general population, and despite attempts from several groups, a hydration status metric based on noninvasive wearable device metrics has not been developed. With wearables, a light source connected to an optical sensor transmits and reflects light through the body. The light sensor detects absorption of the light based on wavelength measurements of the detected light. Absorption of specific wavelengths of light energy is dependent |
| Who can participate | Inclusion Criteria: * Study subject is 18-45 years of age, inclusive * Subject is male or female * If female, subject is not pregnant, planning to get pregnant, or currently breast feeding * Subject is willing to avoid alcohol consumption 24 hours prior to visit(s) * Able to speak, write, and read English * Provision of written consent to participate * Subject is not taking medication that may interfere with the study, as indicated on the general health questionnaire (GHQ) * Subject has no health conditions that would prevent completion of the trial, as indicated on the GHQ * Subject is willing to fast overnight (no food or beverage, only water, \~8- 10 hours) * Subject is willing to refrain from vigorous exercise for 24 hours * Subject is willing to eat the exact same food the day prior t |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | PepsiCo Global R&D |
| Locations | Frisco, Texas, United States; Plano, Texas, United States |
| Start date | 2026-04-01 |
| NCT ID | NCT07520344 |
| Official listing | https://clinicaltrials.gov/study/NCT07520344 |