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Wearable Sensors to Detect Atypical Muscle Activation in Young Infants

The purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and/or identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscl

Condition(s)Neuromuscular Disorders, Motor Development, Muscle Tone
StatusRecruiting
Study typeObservational
SummaryThe purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and/or identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscle activity.
Who can participateInclusion Criteria: * For Infants with low tone: * Hospitalized in the NICU * AND \>38 weeks post-menstrual age * AND abnormal normal brain imaging OR Apgar score \<7 at five minutes with umbilical cord pH (if obtained) \<7.15 * AND 2 or more warning signs for muscle tone or posture using the HNNE short form * AND legal guardian able and willing to give written consent and comply with study procedures * For Infants with typical tone: * Born at 38-41 weeks of gestation * AND hospitalized after birth in the NICU OR well newborn nursery * AND infants with appropriate for gestational age birth weight * AND HNNE exam (short proforma) normal with no warning signs for any parameter * AND legal guardian able and willing to give written consent and comply with study procedures. Exclusion Criteria:
Ages0 Months to 8 Weeks
SexAll
Lead sponsorShirley Ryan AbilityLab
LocationsChicago, Illinois, United States; Chicago, Illinois, United States
Start date2025-06-25
NCT IDNCT06970522
Official listinghttps://clinicaltrials.gov/study/NCT06970522

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