Wrist Denervation Vs Exercise in Wrist Osteoarthritis
A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.
| Condition(s) | Osteoarthritis Wrist |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis. |
| Who can participate | Inclusion Criteria: * Age ≥ 18 years. * Chronic wrist pain (≥6 months) due to Scapholunate advanced collapse (SLAC) / Scaphoid non-union advanced collapse (SNAC) grade 1-3 osteoarthritis. * Radiological signs of osteoarthritis on posteroanterior and lateral radiograph. Exclusion Criteria: * Previous PIN or AIN neurectomy. * Rheumatoid arthritis or other chronic inflammatory arthritis. * Symptomatic osteoarthritis in the distal radio-ulnar (DRU), Scapho-trapezio-trapezoid (STT) or thumb carpometacarpal (CMC) joints. * Ongoing infection. * Inability to co-operate with the follow-up protocol. * Systemic or intra-articular glucocorticoids or intraarticular PRP or Hyaluronic acid injections in the affected joint within 3 months prior to enrollment. |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Karolinska Institutet |
| Locations | Malmö, Sweden; Stockholm, Sweden |
| Start date | 2023-11-15 |
| NCT ID | NCT06098586 |
| Official listing | https://clinicaltrials.gov/study/NCT06098586 |